艾昆纬-提高患者安全性：药物警戒工作流程中早期采用人工智能的范式转变（英）-2024-9页

WhitePaperEnhancingPatientSafety:AParadigmShiftThroughEarlyAIAdoptioninPharmacovigilanceWorkflowsJOANNEVANGELISTA,HeadofOperations&Innovations,USPatientSafetyGenentechMEREDITHKILEY,SeniorManagerOperations&Innovations,USPatientSafetyGenentechMARIEFLANAGAN,DirectorofOfferingManagement,IQVIAVigilanceDetectTableofcontentsIntroduction3AcalltorethinkPatientSupportPrograms(PSPs)3ATHENAinitiativeoverview:collaborativeinnovation4PatientsafetydatadistillingthroughthePVworkflowfaster4Shapingapatient-centricapproach5Thetechnologicalcore:IQVIAVigilanceDetect5Supervisedlearningforcontinuousenhancement5Impactevaluation:unveilingoperationalefficiency6Upstreamimpact6Downstreamimpact6Qualitativeimpact7Navigatingchallenges:thepathforward7Conclusion7Introductioninteraction.Thegoalwasclear–todecreasetheriskofmissedadverseeventsduetohumanerrorandenhanceInthehigh-stakes,ever-evolvinglandscapeofpatientsafetyoutcomes.pharmacovigilance(PV),theimperativetoensurepatientsafetyisspurringinnovativeapproaches.TraditionalPVAcalltorethinkAEreportinginPatientoperationstypicallystartat‘CaseProcessing,’buttheSupportPrograms(PSPs)persistentchallengeofunderreportedadversedrugreactions(ADRs)demandsaparadigmshift.TheFDA’sPatientSupportPrograms(PSPs),whilerichinvaluableestimatethatonly1–10%ofADRsreachtheAdversedata,havetraditionallybeenoverlooke...